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Motor and Plate

Plaque terminale motrice features a highly detailed relief of the terminal bouton, representing acetylcholine-containing vesicles and the specialized subneural apparatus with secondary synaptic clefts for demonstrating electrochemical signaling.

Neuro-Muscular Interface Precision Illustrates the transition from the myelinated axon to the motor nerve ending, including the Schwann cell covering and the adjacent myofibril mitochondria, at a significantly magnified scale for tactile laboratory analysis.

$110.54

Quick Answer: The Motor and Plate is a motor end plate model, an enlarged view of the neuromuscular junction where a motor nerve ending meets a skeletal muscle fibre and triggers it to contract; the title appears to be a misspelling of “motor end plate”. It is used in physiology, pharmacology and nursing teaching.

How the Neuromuscular Junction Works

Every skeletal muscle fibre is controlled by a branch of a motor neuron from the spinal cord or brainstem. Where the branch reaches the fibre, it spreads into a small cluster of terminals lying in shallow grooves on the fibre’s surface. That specialised patch of muscle membrane is the motor end plate, and the whole contact, nerve terminal plus end plate, is the neuromuscular junction.

When an impulse arrives, calcium channels in the nerve terminal open and synaptic vesicles release acetylcholine into the narrow gap between nerve and muscle, the synaptic cleft. The muscle membrane beneath is folded into junctional folds that carry many acetylcholine receptors. When acetylcholine binds, the receptors open, sodium ions flow in and the resulting end plate potential triggers an action potential across the muscle fibre, which then contracts. The enzyme acetylcholinesterase in the cleft breaks acetylcholine down within milliseconds, so each nerve impulse produces a single twitch.

Several drugs, toxins and diseases act here, which gives the model value beyond basic physiology: curare-type muscle relaxants block the receptors, botulinum toxin stops acetylcholine release, and in myasthenia gravis antibodies reduce the number of working receptors. The listing does not state the magnification or which structures are shown. For the same process between two neurons see The Synapse, and the Muscle Fiber Type model places the junction on a whole fibre.

Where It Is Used

  • Physiology lessons on nerve-to-muscle transmission
  • Pharmacology teaching on neuromuscular blocking drugs used in anaesthesia
  • Explaining myasthenia gravis and botulism in nursing and medical foundation courses
  • Comparing the neuromuscular junction with a synapse between neurons

Specifications

Model of Neuromuscular junction (motor end plate), enlarged
Title note “Motor and Plate” read as “motor end plate”
Structures typically shown Nerve terminal, synaptic vesicles, synaptic cleft, junctional folds
Topics Acetylcholine release, receptor binding, end plate potential
Magnification and structures included Confirm at enquiry

Care & Handling

  • Handle the motor end plate model by its base; fine structures such as the nerve fibre and terminal branches are fragile.
  • Dust with a soft brush and avoid wet cleaning around the joins between separately painted parts.
  • Store it covered, away from direct sunlight.

Why Choose LabEquip

Physiology and pharmacology tutors buy an end plate model because so many drugs and disorders act at this one junction, and learners need to see where. LabEquip lists it in biology lab products; use the contact page to ask about magnification.

Frequently Asked Questions

What is the difference between the motor end plate and the neuromuscular junction?

The motor end plate is the specialised region of the muscle fibre membrane beneath the nerve terminal. The neuromuscular junction is the whole connection: the nerve terminal, the synaptic cleft and the motor end plate together.

Which neurotransmitter acts at the motor end plate?

Acetylcholine. It is released from vesicles in the nerve terminal, crosses the synaptic cleft and binds to nicotinic acetylcholine receptors on the end plate, opening channels that start an action potential in the muscle fibre.

Why is the muscle membrane folded at the end plate?

The junctional folds increase the area of membrane under the nerve terminal, so more acetylcholine receptors can be packed in. This makes transmission reliable, so every nerve impulse produces a muscle action potential.

What does acetylcholinesterase do?

It is an enzyme in the synaptic cleft that breaks acetylcholine down into acetate and choline very quickly. This ends each signal, so the muscle relaxes unless another impulse arrives. The choline is taken back into the nerve terminal and reused.

How do muscle relaxants used in surgery work?

Many bind to the acetylcholine receptors on the motor end plate without opening them, so acetylcholine cannot act and the muscles stay relaxed. Their effect wears off or is reversed at the end of the operation.

What happens at the end plate in myasthenia gravis?

The immune system makes antibodies against acetylcholine receptors, reducing the number that work. Muscles then weaken with repeated use, often first in the eyelids and eye muscles, and improve with rest.

Last Updated: September 2026

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